Boundaries of Visualization
Collaboration is everything?


Conventional imaging techniques used in molecular biology often yield unclear and blurry images unless we employ enhanced lighting techniques and control the behavior of light-emitting molecules. To reconstruct the full image and observe fine details, we need to analyze extensive datasets using statistical methods.
In the "Boundaries of Visualization" exhibit, we translate data sets from a novel microscopy technique called MINFLUX into a musical representation using a piano. This interaction results in harmonious sounds and a three-dimensional visualization of the distribution of two different proteins involved in Alzheimer's and Parkinson's diseases within human skin cell mitochondria.*
Mitochondria are particularly fascinating because they were once believed to have originated through a process called biogenesis. Many research findings suggest that mitochondria were originally separate organisms that were absorbed by single-celled organisms to form a cooperative community. This collaboration enabled the development of more complex life forms. This idea, based on symbiogenesis (as proposed by Lynn Margulis), represents a shift away from the traditional model of evolution based on competition. It is also symbolized by combining detailed skin images of different individuals participating in Schmiede 2023. The boundaries will shift further.

* https://doi.org/10.1073/pnas.200936411


Project collaborators:

Martina R. Fröschl, Mehrta Shirzadian, Peter Mindek